catalog number :
MBS839126
products full name :
NUDT16 antibody
products short name :
[NUDT16]
products name syn :
[Polyclonal NUDT16; Anti-NUDT16; Nudix Type Motif 16; Nudt16; Flj31265]
other names :
[NUDT16 protein; U8 snoRNA-decapping enzyme; U8 snoRNA-decapping enzyme; nudix (nucleoside diphosphate linked moiety X)-type motif 16; IDP phosphatase (EC:3.6.1.-); IDPase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; Nudix motif 16; U8 snoRNA-binding protein H29K; m7GpppN-mRNA hydrolase]
products gene name :
[NUDT16]
other gene names :
[NUDT16; NUDT16; IDPase; Nudix motif 16]
uniprot entry name :
NUD16_HUMAN
reactivity :
Human. Other species are not tested.
purity :
NUDT16 antibody was purified by Antigen Affinity chromatography
form :
Liquid in PBS, pH 7.3, with 0.02% NaN 3 and 50% glycerol.
concentration :
0.34mg/ml
storage stability :
4°C for shipping. Upon receipt store at -20°C to -80°C . Avoid repeat freeze-thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:1,000-10,000. IP: 1:500-1:5,000. IHC and IF: 1:20-1:200
other info1 :
Biological Significance: NUDT16 is an RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner.
other info2 :
Immunogen: NUDT16 antibody was raised in Rabbit using Human NUDT16 as the immunogen
products categories :
Proteases, Inhibitors, Purified Polyclonal Antibodies
products description :
Rabbit polyclonal NUDT16 antibody
ncbi acc num :
AAH31215.2
ncbi pathways :
Metabolism Pathway (477135); Metabolism Of Nucleotides Pathway (106263); Phosphate Bond Hydrolysis By NUDT Proteins Pathway (730342); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); RNA Degradation Pathway (117291); RNA Degradation Pathway (116127)
uniprot summary :
NUDT16: RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro). Belongs to the Nudix hydrolase family. Protein type: EC 3.6.1.62; Nucleolus; Hydrolase. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus. Molecular Function: mRNA binding; snoRNA binding; m7G(5 )pppN diphosphatase activity; protein homodimerization activity; metalloexopeptidase activity; GTP binding; manganese ion binding; magnesium ion binding; cobalt ion binding. Biological Process: snoRNA catabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of cell proliferation; mRNA catabolic process; proteolysis; adenosine to inosine editing; IDP catabolic process