antibody

Luteinizing Hormone beta antibody

MBS838284

1 mg

185 USD

monoclonal

mouse

nonconjugated

[M1709LH]

ELISA, flow cytometry, enzyme immunoassay

Antibody

Luteinizing Hormone beta antibody

[Luteinizing Hormone beta]

[Monoclonal Luteinizing Hormone beta; Anti-Luteinizing Hormone beta; Luteinizing Hormone-beta]

[luteinizing hormone beta subunit (LHbeta), partial; Lutropin subunit beta; lutropin subunit beta; luteinizing hormone beta polypeptide; Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-beta]

[LHB; LHB; CGB4; HH23; hLHB; LSH-B; Lutropin beta chain; LH-B; LSH-B; LSH-beta]

LSHB_HUMAN

Monoclonal

IgG1

[M1709LH]

Mouse

Specific for LH beta subunit. Negative for alpha subunit of LH, HCG, and for both alpha and beta subunit of TSH and FSH.

5

Beta-subunit of LH

> 95% pure

Liquid in 50mM NaCl, 10 mM PBS, pH 8.0 with 0.1% NaN 3

24.05 mg/ml

Store at 4 degree C for short term storage, -20 degree C for long term.

ELISA (EIA) or Lateral Flow immunoassay (double antibody test for LH detection).

This antibody can be used as the labelling antibody with MBS838600 as the coating antibody to detect LH

Biological Significance: Luteinizing hormone (LH) is a hormone produced by the anterior pituitary gland. In females, an acute rise of LH called the LH surge triggers ovulation and development of the corpus luteum. In males, where LH had also been called interstitial cell-stimulating hormone (ICSH) it stimulates Leydig cell production of testosterone.

Immunogen: Luteinizing Hormone beta antibody was raised in Mouse using LH as the immunogen

Hormones & Steroids

Mouse monoclonal Luteinizing Hormone beta antibody

4262812

AAD14960.1

Androgen Biosynthesis Pathway (106154); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Glycoprotein Hormones Pathway (160989); GnRH Signaling Pathway (83091); GnRH Signaling Pathway (502); Hormone Ligand-binding Receptors Pathway (106369); Metabolism Pathway (477135)

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]

LHB: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Defects in LHB are a cause of hypogonadism LHB-related (HGON-LHB). Hypogonadism is characterized by infertility and pseudohermaphroditism. Belongs to the glycoprotein hormones subunit beta family. Protein type: Secreted; Hormone; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19q13.32. Cellular Component: extracellular region. Molecular Function: hormone activity; receptor binding. Biological Process: progesterone biosynthetic process; cellular protein metabolic process; cell-cell signaling; male gonad development; peptide hormone processing; signal transduction. Disease: Fertile Eunuch Syndrome

1 mg

185 USD