catalog number :
MBS838237
products full name :
Ly6A/E antibody
products short name :
[Ly6A/E]
products name syn :
[Monoclonal Ly6A/E; Anti-Ly6A/E; LyA/E 6; Ly6E; Sca1; Ly6AE; LyA/E-6; Ly6A/E; Ly6A]
products gene name :
[Ly6A/E]
reactivity :
Mouse Sca-1, an 18kDa member of the LY-6 family of GPI-linked surface proteins
purity :
Ly6A/E antibody was purified by affinity chromatography.
form :
Liquid in aqueous buffer, 0.09% sodium azide, may contain carrier protein stabilizer
concentration :
0.5 mg/ml
storage stability :
Store at 4°C
tested application :
Flow Cytometry (FC/FACS)
app notes :
FC: <= 0.5 ug/test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest
image1 heading :
Flow Cytometry (FC/FACS)
other info1 :
Biological Significance: The D7 monoclonal antibody reacts with mouse Sca-1, an 18 kDa member of the Ly-6 family of GPI-linked surface proteins. D7 reacts with both Ly-6E.1 and Ly-6A.2 molecules expressed by mouse hematopoietic stem cells, myeloid population and peripheral T and B cells. Non-activated splenocytes from Ly-6.2 strains including C57BL, SJL, 129, AKR, and others demonstrate higher frequency of D7-positive cells compared to the Ly-6.1 strains such as BALB/c, C3H, NZB and others. Sca-1 is expressed at high levels upon activation regardless of the Ly-6 haplotype. The Ly-6 family is involved in regulation and function of T cell activation. Sca-1 is a major phenotypic marker for mouse hematopoietic progenitor/stem cell subset.
products categories :
Immunology
products description :
Rat monoclonal Ly6A/E antibody