catalog number :
MBS837895
products full name :
IGJ antibody
products short name :
[IGJ]
products name syn :
[Monoclonal IGJ; Anti-IGJ; IGCJ; JCH]
other names :
[immunoglobulin J chain; Immunoglobulin J chain; immunoglobulin J chain; joining chain of multimeric IgA and IgM]
products gene name :
[IGJ]
other gene names :
[JCHAIN; IGJ; IGJ; JCH; IGCJ; IGCJ]
uniprot entry name :
IGJ_HUMAN
purity :
IGJ antibody was purified by affinity chromatography.
form :
Liquid in PBS, pH 7.3 with 1% BSA,50% Glycerol and 0.02% Sodium Azide.
concentration :
0.63 mg/ml
storage stability :
Upon receipt store at -20°C. Avoid repeat freeze/thaw cycles.
tested application :
Suitable for use in WB and FC.
app notes :
FC: 1:100. WB: 1:2000
image1 heading :
Flow Cytometry (FC/FACS)
image2 heading :
Western Blot (WB)
other info1 :
Biological Significance: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
other info2 :
Immunogen: Full length human recombinant protein of human IGJ (NP_653247) produced in HEK293T
products categories :
Immunology
products description :
Mouse monoclonal IGJ antibody
ncbi acc num :
NP_653247.1
ncbi gb acc num :
NM_144646.3
uniprot summary :
IGJ: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q21. Cellular Component: extracellular space; extracellular region. Molecular Function: peptidoglycan binding; protein homodimerization activity; IgA binding; phosphatidylcholine binding; antigen binding; single-stranded DNA binding. Biological Process: positive regulation of protein oligomerization; retinal homeostasis; adaptive immune response; glomerular filtration; antibacterial humoral response; innate immune response; immune response