catalog number :
MBS837654
products full name :
NeuN antibody
products short name :
NeuN
products name syn :
Polyclonal NeuN; Anti-NeuN; Fox 3; Fox-3; Neu-N; Neu N
other names :
RNA binding protein fox-1 homolog 3 isoform 3; RNA binding protein fox-1 homolog 3; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog (C. elegans) 3; Fox-1 homolog C; Hexaribonucleotide-binding protein 3; Fox-3; Neuronal nuclei; NeuN
products gene name :
NeuN
other gene names :
Rbfox3; Rbfox3; NeuN; Fox-3; Hrnbp3; Neuna60; D11Bwg0517e; Hrnbp3; Fox-3; NeuN
uniprot entry name :
RFOX3_MOUSE
purity :
NeuN antibody was purified by affinity chromatography.
form :
Phosphate buffered (10mM) isotonic (0.9%, w/v) saline (PBS, pH7.2) with 50% (v/v) glycerol and 0.02% sodium azide as preservative.
concentration :
100 ug/ml
storage stability :
Store at 4 degree C. Avoid repeated freeze/thaw cycles. Protect from light.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC)
app notes :
ICC: 1:2,000 - 1:5,000. IHC: 11:2,000 - 1:5,000
other info1 :
Biological Significance: The vast majority of neurons are strongly NeuN positive, and NeuN immunoreactivity has been widely used to identify neurons is tissue culture and in sections and to measure the neuron/glial ratio in brain regions. NeuN immunoreactivity becomes obvious as neurons mature, typically after they have downregulated expression of Doublecortin, a marker seen in the earliest stages of neuronal development.
other info2 :
Immunogen: Synthetic peptide-keyhole limpet hemocyanin (KLH) conjugate.
products categories :
Neuroscience; Purified Polyclonal Antibodies
products description :
Affinity purified Chicken polyclonal NeuN antibody
ncbi acc num :
NP_001020102
ncbi gb acc num :
NM_001024931.2
uniprot summary :
NeuN: RNA-binding protein that regulates alternative splicing events. Protein type: RNA processing; DNA-binding; RNA splicing. Cellular Component: cell soma; cytoplasm; perikaryon; intracellular; nucleus. Molecular Function: protein binding; DNA binding; nucleic acid binding; RNA binding; nucleotide binding. Biological Process: regulation of RNA splicing; RNA splicing; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome