FGF 18 antibody | MyBioSource MBS837298 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FGF 18 antibody

catalog :

MBS837298

quantity :

0.1 mg

price :

665 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS837298

products type :

Antibody

products full name :

FGF 18 antibody

products short name :

FGF 18

products name syn :

Polyclonal FGF 18; Anti-FGF 18; FGF -18; FGF 18; FGF-18; Fibroblast Growth Factor 18

other names :

fibroblast growth factor 18; Fibroblast growth factor 18; fibroblast growth factor 18; fibroblast growth factor 18; zFGF5

products gene name :

FGF 18

other gene names :

FGF18; FGF18; ZFGF5; FGF-18; FGF-18

uniprot entry name :

FGF18_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

207

purity :

FGF 18 antibody was purified by affinity purification.

form :

Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

concentration :

500 ug/ml

storage stability :

Store at -20 degree C. For long-term storage, aliquot and freeze at -70 degree C. Avoid repeated freeze/thaw cycles.

tested application :

Western Blot (WB)

app notes :

WB: 0.5-4 ug/ml

other info1 :

Biological Significance: The FGFs plays an important role in regulating tissue growth, morphogenesis and tissue repair. FGF 18 is a newly discovered heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors.

other info2 :

Immunogen: FGF 18 antibody was raised in Rabbit using E Coli expressed recombinant human FGF-18 as the immunogen.

products categories :

Cytokines & Growth Factors

products description :

Rabbit polyclonal FGF 18 antibody

ncbi gi num :

4503695

ncbi acc num :

NP_003853.1

ncbi gb acc num :

NM_003862.2

uniprot acc num :

O76093

ncbi mol weight :

23,989 Da

ncbi pathways :

Activated Point Mutants Of FGFR2 Pathway (645281); Adaptive Immune System Pathway (366160); Constitutive Signaling By Aberrant PI3K In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Diseases Of Signal Transduction Pathway (1183518); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR1 Pathway (1183557)

ncbi summary :

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]

uniprot summary :

FGF18: Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation. Belongs to the heparin-binding growth factors family. Protein type: Secreted; Cytokine; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q34. Cellular Component: extracellular space; nucleolus; extracellular region. Molecular Function: growth factor activity; type 2 fibroblast growth factor receptor binding; type 1 fibroblast growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; nervous system development; regulation of endothelial cell proliferation; intramembranous ossification; anatomical structure morphogenesis; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; chondrocyte development; signal transduction; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of MAP kinase activity; positive regulation of chondrocyte differentiation; cell-cell signaling; positive regulation of cell proliferation; insulin receptor signaling pathway; innate immune response; angiogenesis; lung development; endochondral ossification

size1 :

0.1 mg

price1 :

665 USD

more info or order :

MyBioSource product webpage