catalog number :
MBS835967
products type :
Recombinant Protein
products full name :
PTP1B protein
products short name :
PTP1B
products name syn :
PTPN1 protein; PTPB 1 protein; Protein Tyrosine Phosphatase Non Receptor Type-1; PTPB-1; Protein Tyrosine Phosphatase 1B protein; PTP1B protein; PTPB 1; PTP-1B protein; EC 3.1.3.48 protein; PTP1B; PTPB-1 protein; Protein tyrosine phosphatase non-receptor type 1 protein; Protein-tyrosine phosphatase1B protein; Tyrosine-protein phosphatase non-receptor type 1 protein
other names :
protein tyrosine phosphatase 1b; Tyrosine-protein phosphatase non-receptor type; tyrosine-protein phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1
products gene name :
PTP1B
other gene names :
ptpn1; ptpn1; ptp1b; wu:fk54h03
uniprot entry name :
B0S5X5_DANRE
sequence :
MEMEKEFEQI DKSGSWAAIY QDIRHEASDF PCRVAKLPKN KNRNRYRDVS PFDHSRIKLH QEDNDYINAS LIKMEEAQRS YILTQGPLPN TCGHFWEMVW EQKSRGVVML NRVMEKGSLK CAQYWPQKEE KEMIFEDTNL KLTLISEDIK SYYTVRQLEL ENLTTQETRE ILHFHYTTWP DFGVPESPAS FLNFLFKVRE SGSLSPEHGP VVVHCSAGIG RSGTFCLADT CLLLMDKRKD PSSVDIKKVL LEMRKFRMGL IQTADQLRFS YLAVIEGAKF IMGDSSVQDQ WKELSHEDLE PPPEHIPPPP RPPKRILEPH N
form :
Supplied as a liquid in 25 mM Tris-HCl, pH7.5, containing 2 mM beta-mercaptoethanol, 1 mM EDTA.1mMDTT, and 20% glycerol.
storage stability :
Store at 4 degree C for short term storage (1/2 weeks). Aliquot and store at -20 degree C or - 70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
SDS-PAGE
app notes :
One unit will hydrolyze 1nanomole of p-nitrophenyl-phosphatate per minute at pH 7.4 at 37 DEG C using 10mM of substrate
other info1 :
Protein Type: Recombinant. Biological Significance: The protein coding region of the catalytic domain of PTP-1B (amino acids 1-321) was cloned into an E Coli expression vector. The catalytic domain of PTP-1B was overexpressed in E Coli as a soluble protein, and it was purified by conventional column chromatographic techniques. Bioactivity: 10,000units/mg of PTP1B
other info2 :
Expression System: E Coli
products categories :
Signal Transduction
products description :
Purified recombinant Human PTP1B protein
ncbi acc num :
CAQ14262.1
ncbi mol weight :
37.3 kDa (321 aa)
ncbi pathways :
Adherens Junction Pathway 119268!!Adherens Junction Pathway 481!!Cytokine Signaling In Immune System Pathway 1171216!!ERK1 - ERK2 MAPK Cascade Pathway 198962!!FGF Signaling Pathway 198948!!Growth Hormone Receptor Signaling Pathway 1171233!!Hemostasis Pathway 1171004!!Immune System Pathway 1171092!!Insulin Signaling Pathway 921015!!Insulin Signaling Pathway 119273