product summary
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company name :
MyBioSource
product type :
antibody
product name :
MAFF antibody
catalog :
MBS835421
quantity :
0.1 mg
price :
370 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot
more info or order :
image
image 1 :
MAFF antibody (MBS835421) used at 0.2-1 ug/ml to detect target protein.
product information
catalog number :
MBS835421
products type :
Antibody
products full name :
MAFF antibody
products short name :
[MAFF]
products name syn :
[Polyclonal MAFF; Anti-MAFF; v-maf musculoaponeurotic fibrosarcoma oncogene homolog F; avian]
other names :
[Transcription factor MafF; transcription factor MafF; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F; U-Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F]
products gene name :
[MAFF]
other gene names :
[MAFF; MAFF; U-MAF; hMafF]
uniprot entry name :
MAFF_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit , Rat, Zebrafish
sequence length :
135
form :
Lyophilized powder. Reconstitute with 100 uL distilled water for a final concentration of 1.0 mg/ml in PBS with 2% sucrose.
concentration :
1 mg/ml
storage stability :
Ships ambient or refrigerated. Upon receipt store at 4°C for short term, -20°C for long term.
tested application :
Suitable for use in WB.
app notes :
WB: 5 ug/ml
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Synthetic peptide directed toward the N terminal region of human MAFF. Biological Significance: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.
products categories :
Protein Modification & Stress Response
products description :
Rabbit polyclonal MAFF antibody
ncbi gi num :
23111003
ncbi acc num :
NP_690617
ncbi gb acc num :
NM_152878.1
uniprot acc num :
Q9ULX9
ncbi pathways :
Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); Hemostasis Pathway (106028); Myometrial Relaxation And Contraction Pathways (198759)
ncbi summary :
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
uniprot summary :
MAFF: Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response. Belongs to the bZIP family. Maf subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: nucleoplasm. Molecular Function: sequence-specific DNA binding; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; in utero embryonic development; regulation of epidermal cell differentiation; parturition; blood coagulation
size1 :
0.1 mg
price1 :
370 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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