catalog number :
MBS835379
products full name :
Inhibin beta A antibody
products short name :
[Inhibin beta A]
products name syn :
[Polyclonal Inhibin beta A; Anti-Inhibin beta A; FSH-releasing protein; follicle-stimulating hormone-releasing protein; erythroid differentiation factor; inhibin beta A (activin A activin AB alpha polypeptide); INHBA; FRP; inhibin beta A chain; EDF; activin beta-A chain]
other names :
[inhibin beta A, partial; Inhibin beta A; Inhibin beta A]
other gene names :
[INHBA]
uniprot entry name :
K4HH04_9SAUR
reactivity :
Human; Predicted: Mouse, Rat, Cat, Pig, Chicken, Sheep, Bovine
purity :
Inhibin beta A antibody was purified by antigen-affinity chromatography
form :
Liquid in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
storage stability :
Keep as concentrated solution. 4 degree C shipping. Upon receipt, aliquot and store at -20 degree C.
tested application :
Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
app notes :
IF:1:100-1:500. ICC:1:100-1:500. IHC-P: 1:100-1:500. WB: 1:500-1:3000
image1 heading :
Immunofluorescence (IF)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Biological Significance: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
other info2 :
Immunogen: Synthetic peptide corresponding to a region within amino acids 362 and 426 of Inhibin beta A.
products categories :
DNA Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal Inhibin beta A antibody
ncbi acc num :
AFR13118.1