catalog number :
MBS835354
products full name :
Syntaxin 5 antibody
products short name :
[Syntaxin 5]
products name syn :
[Polyclonal Syntaxin 5; Anti-Syntaxin 5; STX5A; Syntaxin 5; Syntaxin -5; syntaxin-5; syntaxin 5; SED5; syntaxin 5A; STX5]
other names :
[syntaxin 5; Syntaxin-5; syntaxin-5; syntaxin 5]
other gene names :
[STX5; STX5; SED5; STX5A; STX5A]
uniprot entry name :
STX5_HUMAN
reactivity :
Xenopus laevis, Pig, Rhesus Monkey, Bovine.
purity :
Syntaxin 5 antibody was purified by antigen-affinity chromatography
form :
Affinity purified liquid in 100mM Tris, pH 7.0, with 100 mM Glycine, 20% Glycerol, and 0.01% Thimerosal.
concentration :
1.01 mg/ml
storage stability :
Store at 4°C for short term, -20°C for long term. Avoid repeat freeze-thaws.
tested application :
Suitable for use in ICC/IF, IHC, WB.
app notes :
ICC/IFF (1:100-1:1000). IHC (1:100-1,000). WB (1:100-1:10,000)
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunofluorescence (IF)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
Immunohistochemical staining of paraffin-embedded MCF7 xenograft using Syntaxin 5 antibody at a dilution of 1:500
other info1 :
Immunogen: Recombinant protein encompassing a propietary sequence within the center region of human Syntaxin 5. Biological Significance: Syntaxin 5 mediates endoplasmic reticulum to Golgi transport.
products categories :
Cell Biology; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal Syntaxin 5 antibody
ncbi acc num :
AAC71078.1
ncbi pathways :
SNARE Interactions In Vesicular Transport Pathway (83057); SNARE Interactions In Vesicular Transport Pathway (467)
ncbi summary :
This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
uniprot summary :
STX5: Mediates endoplasmic reticulum to Golgi transport. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 11q12.3. Cellular Component: nucleoplasm; Golgi membrane; SNARE complex; Golgi apparatus; ER-Golgi intermediate compartment membrane; endoplasmic reticulum; integral to membrane; vesicle. Molecular Function: SNAP receptor activity; SNARE binding; protein binding; protein N-terminus binding. Biological Process: vesicle fusion; intracellular protein transport; ER to Golgi vesicle-mediated transport; vesicle docking; positive regulation of protein catabolic process; vesicle fusion with Golgi apparatus; retrograde transport, endosome to Golgi