product summary
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company name :
MyBioSource
product type :
antibody
product name :
GABRP antibody
catalog :
MBS835317
quantity :
0.1 mg
price :
370 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS835317 image 1
GABRP antibody (MBS835317) used at 0.2-1 ug/ml to detect target protein.
product information
catalog number :
MBS835317
products type :
Antibody
products full name :
GABRP antibody
products short name :
[GABRP]
products name syn :
[Polyclonal GABRP; Anti-GABRP; pi; GABA A receptor; gamma-aminobutyric acid]
other names :
[gamma-aminobutyric acid receptor subunit pi isoform 1; Gamma-aminobutyric acid receptor subunit pi; gamma-aminobutyric acid receptor subunit pi; gamma-aminobutyric acid (GABA) A receptor, pi; GABA(A) receptor subunit pi]
products gene name :
[GABRP]
other gene names :
[GABRP; GABRP]
uniprot entry name :
GBRP_HUMAN
clonality :
Polyclonal
host :
Rabbit
form :
Lyophilized powder. Reconstitute with 100 ul of distilled water for final concentration of 1 mg/ml in PBS buffer with 2% sucrose
storage stability :
Ships ambient or refrigerated. 4°C short term/-20°C long term. Avoid repeat freeze-thaw cycles.
tested application :
Western Blot (WB)
app notes :
Optimal conditions to be determined by the end user
image1 heading :
Western Blot (WB)
other info1 :
Biological Significance: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
other info2 :
Immunogen: Synthetic peptide directed towards the N-terminal of human GABRP
products categories :
Signal Transduction
products description :
Rabbit polyclonal GABRP antibody
ncbi gi num :
7657106
ncbi acc num :
NP_055026
ncbi gb acc num :
NM_014211.2
uniprot acc num :
O00591
ncbi mol weight :
50,640 Da
ncbi pathways :
GABAergic Synapse Pathway (377263); GABAergic Synapse Pathway (377129); Morphine Addiction Pathway (552665); Morphine Addiction Pathway (554808); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Nicotine Addiction Pathway (583255); Nicotine Addiction Pathway (584676); Retrograde Endocannabinoid Signaling Pathway (537443); Retrograde Endocannabinoid Signaling Pathway (539806)
ncbi summary :
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
uniprot summary :
GABRP: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRP sub-subfamily. Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 5q35.1. Cellular Component: postsynaptic membrane; cell junction. Molecular Function: chloride channel activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity. Biological Process: signal transduction
size1 :
0.1 mg
price1 :
370 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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