alpha 1 Microglobulin mAb | MyBioSource MBS834963 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

alpha 1 Microglobulin mAb

catalog :

MBS834963

quantity :

0.1 mL

price :

375 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[10A12]

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS834963

products type :

Antibody

products full name :

alpha 1 Microglobulin mAb

products short name :

[alpha 1 Microglobulin]

products name syn :

[Monoclonal alpha 1 Microglobulin; Anti-alpha 1 Microglobulin; AMBP; alpha-1-microglobulin/bikunin precursor; A1M; alpha-1 microglobulin; alpha 1 microglobulin/bikunin; alpha-1-microglobulin/bikunin; Alpha-1 microglobulin/bikunin; ASPI; bikunin; BOS_9342; complex-forming glycoprotein heterogeneous in charge; EDC1; growth-inhibiting protein 19; HCP; HI30; HI-30; iatil; ilil; inter-alpha-trypsin inhibitor light chain; inter-alpha-trypsin inhibitor (protein HC); light; Intin4; ITI; Itil; itilc; polyprotein; protein AMBP; protein AMBP-like; protein HC; RP23-6H1.3; trypstatin; ulinastatin; Urinary Trypsin Inhibitor; uristatin; uronic-acid-rich protein; UTI]

other names :

[alpha-1-microglobulin, partial; Protein AMBP; protein AMBP; alpha-1-microglobulin/bikunin precursor; Alpha-1-microglobulin; Protein HC]

other gene names :

[AMBP; AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; HCP; ITIL; Protein HC; ITI-LC]

uniprot entry name :

AMBP_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

[10A12]

host :

Mouse

reactivity :

Human

sequence length :

151

purity :

alpha 1 Microglobulin antibody was purified by ammonium sulfate precipitation

form :

Liquid in HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

concentration :

1mg/ml

storage stability :

Upon receipt store at -20 degree C. Avoid freeze/thaw cycles. Shipping: Ships at 4 degree C .

tested application :

ELISA (EIA), Western Blot (WB)

app notes :

WB: 1:2000

image1 heading :

Western Blot (WB)

other info1 :

Biological Significance: alpha1-Microglobulin (protein HC) is a lipocalin with immunosuppressive properties. The lipocalins are a family of proteins which transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Well known lipocalins are alpha1-microglobulin, alpha-1-acid glycoprotein (orosomucoid), apolipoprotein D, beta-lactoglobulin, and complement component C8 gamma chain etc. A gene in the lipocalin cluster encodes alpha1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins secreted to the blood separately.

other info2 :

Immunogen: alpha 1 Microglobulin antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

products categories :

Cell Biology

products description :

Mouse monoclonal alpha 1 Microglobulin antibody

ncbi gi num :

579676

ncbi acc num :

CAA38587.1

uniprot acc num :

P02760

ncbi pathways :

Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600); Vesicle-mediated Transport Pathway (1183600)

ncbi summary :

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]

uniprot summary :

AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9q32-q33. Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; plasma membrane; extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; heme binding; calcium oxalate binding; IgA binding; calcium channel inhibitor activity. Biological Process: negative regulation of JNK cascade; receptor-mediated endocytosis; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage

size1 :

0.1 mL

price1 :

375 USD

more info or order :

MyBioSource product webpage