antibody

Amyloid beta 40 antibody

MBS834875

0.1 mL

375 USD

monoclonal

mouse

nonconjugated

[32A1]

western blot, ELISA, enzyme immunoassay

Antibody

Amyloid beta 40 antibody

[Amyloid beta 40]

[Monoclonal Amyloid beta 40; Anti-Amyloid beta 40; APP; amyloid beta (A4) precursor protein; AAA; ABETA; ABPP; ad1; Adap; AG; alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; amyloid A4; amyloid beta (A4) precursor protein (peptidase nexin-2; Alzheimer disease); amyloid beta (A4) precursor protein (peptidase nexin-II; amyloid beta (A4) precursor protein (protease nexin-II; amyloid beta A4 protein; Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimers disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4); amyloidogenic glycoprotein; amyloid precursor protein; amyloid protein; appi; appican; app-PH; app-PI; app-PJ; app-PK; app-PL; app-PM; app-PO; app-PP; app-PQ; approximated; beta-amyloid peptide; beta-amyloid precursor protein; beta-amyloid precursor protein A; betaApp; BOS_589; cerebral vascular amyloid peptide; CG42318-PH; CG42318-PI; CG42318-PJ; CG42318-PK; CG42318-PL; CG42318-PM; CG42318-PO; CG42318-PP; CG42318-PQ; CR32097; CTFgamma; CVAP; Dmel_CG17144; Dmel_CG42318; Dmel_CG5620; peptidase nexin-II; pn2; PN-II; preA4; protease nexin II; protease nexin-II]

Monoclonal

IgG2b kappa

[32A1]

Mouse

Human

Amyloid beta 40 antibody was purified by ammonium sulfate precipitation

Liquid in HEPES, with 150mM NaCl, 0.01% BSA, 0.03% NaN 3 , and 50% Glycerol.

100ul per vial

4 degree C shipping. Upon receipt store at -20 degree C.

ELISA (EIA), Western Blot (WB)

WB: 1:2000

Western Blot (WB)

Biological Significance: Amyloid beta (Abeta or A beta) is a protein fragment of 39-43 amino acids that is the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Abeta is formed after sequential cleavage of the amyloid precursor protein (APP, transmembrane glycoprotein) by the beta- and gamma-secretases. The major species generated are Abeta40 and Abeta42. The latter is more hydrophobic and more apt to aggregate and thus is considered to be primarily pathogenic, consistent with the phenotype of the major familial AD-causing mutations. Increases in either total Abeta levels or the relative concentration of the 42-amino acid form have been implicated in the pathogenesis of both familial and sporadic Alzheimer's disease. The 42-mers are the most amyloidogenic form of the peptide.

Immunogen: synthetic peptide

Neuroscience

Mouse monoclonal Amyloid beta 40 antibody

0.1 mL

375 USD