product summary
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company name :
MyBioSource
product type :
antibody
product name :
GFAP antibody
catalog :
MBS834682
quantity :
0.1 mL
price :
425 USD
clonality :
polyclonal
host :
guinea pigs
conjugate :
nonconjugated
reactivity :
human, rat, cow
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
citations: 1
Reference
Tensaouti Y, Stephanz E, Yu T, Kernie S. ApoE Regulates the Development of Adult Newborn Hippocampal Neurons. Eneuro. 2018;5: pubmed publisher
product information
catalog number :
MBS834682
products type :
Antibody
products full name :
GFAP antibody
products short name :
GFAP
products name syn :
Polyclonal GFAP; Anti-GFAP; Glial Filament Protein; Glial Fibrillary Acid Protein; Glial marker
other names :
glial fibrillary acidic protein; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein
products gene name :
GFAP
other gene names :
GFAP; GFAP; ALXDRD; GFAP
uniprot entry name :
GFAP_HUMAN
clonality :
Polyclonal
host :
Guinea Pig
reactivity :
Human, Bovine, Rat
sequence length :
432
specificity :
Bovine GFP
form :
Liquid with 0.09% sodium azide as preservative.
concentration :
100ul
storage stability :
4 degree C.
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
app notes :
IHC: 1:100. IHC-P: 1:50. WB: 1:2000
other info1 :
Biological Significance: GFP is an intermediate filament. GFP and vimentin are linked to the same filament network; they are localized in the same filaments. mRNAs encoding the glial intermediate filament protein are spatially dispersed in the glial cell cytoplasm close to the location of the glial filaments.
other info2 :
Immunogen: Gliafilament protein purified from bovine spinal cord.
products categories :
Cell Biology
products description :
Guinea Pig polyclonal GFAP antibody
ncbi gi num :
251802
ncbi acc num :
AAB22581.1
uniprot acc num :
P14136
ncbi mol weight :
49,508 Da
ncbi pathways :
Neural Crest Differentiation Pathway (672460); Nuclear Signaling By ERBB4 Pathway (530744); Signal Transduction Pathway (477114); Signaling By ERBB4 Pathway (530741); Spinal Cord Injury Pathway (739007)
ncbi summary :
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
uniprot summary :
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: membrane; cytoplasm; intermediate filament; cytosol. Molecular Function: integrin binding; structural constituent of cytoskeleton; kinase binding. Biological Process: extracellular matrix organization and biogenesis; Bergmann glial cell differentiation; regulation of neurotransmitter uptake; response to wounding; neurite regeneration; intermediate filament organization; astrocyte development. Disease: Alexander Disease
size1 :
0.1 mL
price1 :
425 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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