catalog number :
MBS834539
products full name :
Mouse Monoclonal EB1+EB2+EB3 antibody
products short name :
EB1+EB2+EB3
products name syn :
Monoclonal EB1; EB2; Anti EB1; EB3; EB1; EB+EB2+EB3 1; EB+EB2+EB3-1; EB1+EB2+EB3
products gene name :
EB1+EB2+EB3
reactivity :
Mouse EB1+EB2+EB3
purity :
EB1, EB2, EB3 antibody was purified using Protein G chromatography.
form :
Supplied in PBS buffer containing 0.1% sodium azide as a preservative
storage stability :
Store at 4 degree C for short term. For long term storage store at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB)
app notes :
IP: 2 ug/ml. IF: 1:100-1:1000. WB: 1:500-1:5000
other info1 :
Biological Significance: EB1 was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. The function of EB2 is unknown. EB3 protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.
other info2 :
Biohazard Information: This product contains 0.1% sodium azide which is hazardous. Immunogen: Recombinant mouse EB1. Immunogen Information: Antibody was raised in Mouse using Mouse EB1 and GST fusion protein as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal EB1 + EB2 + EB3 antibody