product summary
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company name :
MyBioSource
product type :
antibody
product name :
TMOD1 antibody
catalog :
MBS834528
quantity :
0.1 mL
price :
760 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[2C2]
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
image
image 1 :
MyBioSource MBS834528 image 1
Immunofluorescent staining of COS7 cells transiently transfected with recombinant TMOD1 protein using TMOD1 antibody
image 2 :
MyBioSource MBS834528 image 2
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TMOD1 protein (Right) or empty vector (Left) detected with TMOD1 antibody
image 3 :
MyBioSource MBS834528 image 3
Immunohistochemical analysis of TMOD1 protein in paraffin embedded Human tonsil tissue using TMOD1 antibody
product information
catalog number :
MBS834528
products type :
Antibody
products full name :
TMOD1 antibody
products short name :
[TMOD1]
products name syn :
[Monoclonal TMOD1; Anti-TMOD1; D9S57E; ETMOD; TMOD; TMOD1; TMOD 1; TMOD-1]
other names :
[tropomodulin-1; Tropomodulin-1; tropomodulin-1; tropomodulin 1; Erythrocyte tropomodulin; E-Tmod]
products gene name :
[TMOD1]
other gene names :
[Tmod1; Tmod1; Tmod; E-Tmod; Tmod; E-Tmod]
uniprot entry name :
TMOD1_MOUSE
clonality :
Monoclonal
isotype :
IgG2b
clone :
[2C2]
host :
Mouse
reactivity :
Human, Rat, Monkey, Mouse
sequence length :
359
purity :
TMOD1 antibody was purified by affinity chromatography.
form :
Liquid in PBS, pH 7.3 with 1% BSA, 50% Glycerol and 0.02% NaN 3
concentration :
0.86 mg/ml
storage stability :
Shipping: Blue ice. Upon receipt store at -20°C. Avoid freeze/thaw cycles.
tested application :
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
IF: 1:100. IHC: 1:150. WB: 1:500-2000
image1 heading :
Immunofluorescence (IF)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Biological Significance: This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton.
other info2 :
Immunogen: Full length human recombinant protein of human TMOD1 produced in HEK293T cell.
products categories :
Cell Biology
products description :
Mouse monoclonal TMOD1 antibody
ncbi gi num :
11230778
ncbi acc num :
NP_068683.1
ncbi gb acc num :
NM_021883.2
uniprot acc num :
P49813
ncbi pathways :
Muscle Contraction Pathway (1168140); Striated Muscle Contraction Pathway (1168141); Striated Muscle Contraction Pathway (198348)
uniprot summary :
TMOD1: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. Belongs to the tropomodulin family. Protein type: Cytoskeletal; Cell development/differentiation; Motility/polarity/chemotaxis; Contractile. Cellular Component: cortical cytoskeleton; signalosome; sarcomere; cytoskeleton; membrane; myofibril; cytoplasm; nucleus; striated muscle thin filament. Molecular Function: actin filament binding; tropomyosin binding; actin binding. Biological Process: muscle thick filament assembly; myofibril assembly; muscle contraction; adult locomotory behavior; actin filament organization; pointed-end actin filament capping
size1 :
0.1 mL
price1 :
760 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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