catalog number :
MBS834269
products full name :
SAP30BP antibody
products short name :
[SAP30BP]
products name syn :
[Polyclonal SAP30BP; Anti-SAP30BP; SAPBP 30; SAPBP-30; SAP30BP; SAP30 binding protein]
other names :
[SAP30-binding protein isoform 2; SAP30-binding protein; SAP30-binding protein; SAP30 binding protein; Transcriptional regulator protein HCNGP]
products gene name :
[SAP30BP]
other gene names :
[SAP30BP; SAP30BP; HTRG; HTRP; HCNGP]
uniprot entry name :
S30BP_HUMAN
reactivity :
Human; Predicted: Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish
form :
Purified antibody supplied as a liquid in PBS buffer with 0.09% NaN3 and 2% sucrose.
storage stability :
Store at 4°C short term, -20°C long term. Avoid repeat freeze-thaws.
tested application :
Western Blot (WB)
app notes :
WB: 1.25 ug/ml
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: Synthetic peptide directed towards the C-terminal region of human SAP30BP.
products categories :
Signal Transduction
products description :
SAP30BP is a component of a histone deacetylase complex conserved among eukaryotic organisms. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones due to the inability of the histone binding proteins RbAp46 and RbAp48 to gain access to nucleosomal histones.
ncbi gb acc num :
NM_013260.6
ncbi pathways :
Epigenetic Regulation Of Gene Expression Pathway (1127671); Gene Expression Pathway (105937); Negative Epigenetic Regulation Of RRNA Expression Pathway (1127674); NoRC Negatively Regulates RRNA Expression Pathway (1127676)
uniprot summary :
SAP30BP: Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes. Belongs to the HCNGP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 17q25.1. Cellular Component: nucleoplasm; intermediate filament cytoskeleton; nucleus. Molecular Function: protein binding. Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; apoptosis; gene expression; regulation of gene expression, epigenetic