catalog number :
MBS834171
products full name :
Glutathione Peroxidase I antibody
products short name :
[Glutathione Peroxidase I]
products name syn :
[Monoclonal Glutathione Peroxidase I; Anti-Glutathione Peroxidase I; GPX1; glutathione peroxidase 1; AL033363; BOS_20918; cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase type 2; Gpx; GPx-1; GPXD; GSHPx; gshpx1; GSHPx-1; putative glutathione peroxidase; TNeu078a18.1]
reactivity :
Human, Mouse, Rat
purity :
Glutathione Peroxidase I antibody was purified by ammonium sulfate precipitation
form :
Liquid in HEPES with 150mM NaCl, 0.01% BSA, 0.03% NaN3, and 50% Glycerol
storage stability :
4°C shipping. Upon receipt store at -20°C
tested application :
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP)
app notes :
WB: 1: 5000. IP: 1 ul
image1 heading :
Western Blot (WB)
other info1 :
Biological Significance: Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPxfamily to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxylipids in low density lipoprotein orthymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.
other info2 :
Immunogen: Recombinant mouse protein purified from E.coli
products categories :
Signal Transduction
products description :
Mouse monoclonal Glutathione Peroxidase I antibody