catalog number :
MBS833921
products full name :
Gja4 antibody
products short name :
[Gja4]
products name syn :
[Polyclonal Gja4; Anti-Gja4; Gja 4; Gja-4; AW558810; 37kDa; Cnx37; AU020209; Cx37; RP23-347B4.3; Gja4; gap junction protein; alpha 4]
other names :
[gap junction alpha-4 protein; Gap junction alpha-4 protein; gap junction alpha-4 protein; gap junction protein, alpha 4, 37kDa; Connexin-37; Cx37]
products gene name :
[Gja4]
other gene names :
[GJA4; GJA4; CX37; Cx37]
uniprot entry name :
CXA4_HUMAN
reactivity :
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
form :
Lyophilized powder. Reconstitute with 100 uL of distilled water for a final concentration of 1mg/mL in PBS buffer with 2% Sucrose.
storage stability :
Ships ambient or refrigerated. Upon receipt store at 4°C short term, -20°C for long term. Avoid repeat freeze-thaws.
tested application :
Western Blot (WB)
image1 heading :
Western Blot (WB)
other info1 :
Biological Significance: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
other info2 :
Immunogen: Synthetic peptide corresponding to a region of mouse Gja4
products categories :
Cell Biology
products description :
Rabbit polyclonal Gja4 antibody
ncbi gb acc num :
NM_002060.2
ncbi pathways :
Calcium Regulation In The Cardiac Cell Pathway (198906); Gap Junction Assembly Pathway (105928); Gap Junction Trafficking Pathway (105927); Gap Junction Trafficking And Regulation Pathway (105926); Membrane Trafficking Pathway (106160); Ovarian Infertility Genes Pathway (198801); Vesicle-mediated Transport Pathway (1183600)
ncbi summary :
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008]
uniprot summary :
GJA4: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion. Chromosomal Location of Human Ortholog: 1p35.1. Cellular Component: connexon complex; integral to plasma membrane; gap junction. Molecular Function: protein binding. Biological Process: blood vessel development; intercellular junction assembly; cell-cell signaling; transport; calcium ion transport; response to pain