product summary
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company name :
MyBioSource
product type :
antibody
product name :
SHP2 antibody
catalog :
MBS833852
quantity :
0.1 mL
price :
395 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5F2
application :
western blot, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS833852
products type :
Antibody
products full name :
SHP2 antibody
products short name :
SHP2
products name syn :
Monoclonal SHP2; Anti-SHP2; PTPN11; protein tyrosine phosphatase; non-receptor type 11; BOS_16688; BPTP3; CFC; cSH-PTP2; encodes catalytic domain; non-receptor type protein tyrosine phosphatase SHP2; NS1; null; phosphotyrosyl-protein phosphatase; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase SH-PTP2; protein-tyrosine phosphatase SYP; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; SHP-2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase; SH-PTP3; SYP; tyrosine-protein phosphatase non-receptor type 11
other names :
shatterproof 2; BnaA05g02990D protein; BnaA05g02990D protein
products gene name :
SHP2
other gene names :
SHP2
uniprot entry name :
B1PHV6_BRANA
clonality :
Monoclonal
isotype :
IgG1 kappa
clone :
5F2
host :
Mouse
reactivity :
Human, Mouse, Rat
sequence length :
244
purity :
SHP2 antibody was purified by ammonium sulfate precipitation
form :
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
storage stability :
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles
tested application :
Western Blot (WB), Immunoprecipitation (IP)
app notes :
WB: 1:2000. IP: 1 ul
other info1 :
Biological Significance: SHP2 is a tyrosine phosphatase containing two tandem SH2 (src homology 2) domains. Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Together with tyrosine kinases, PTPs regulate the phosphorylation state of many important signaling molecules. SHP1 and SHP2 represent a subfamily of non-transmembrane PTPs that contain two SH2 domains followed by a PTP domain. Tyrosine phosphorylation of SHP2 is required for normal ERK activation in response to some growth factors. In the inactive state, the N-terminal SH2 domain binds the PTP domain and blocks access of potential substrates to the active site. This auto-inhibition is relieved by the binding of phosphopeptides to SH2 domain, resulting in activation of phostphatase activity.
other info2 :
Immunogen: SHP2 antibody was raised in Mouse using a recombinant human GST-SHP2 protein purified from E Coli as the immunogen
products categories :
Signal Transduction
products description :
Mouse monoclonal SHP2 antibody
ncbi gi num :
169117067
ncbi acc num :
ACA42768.1
ncbi mol weight :
28,006 Da
size1 :
0.1 mL
price1 :
395 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

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