catalog number :
MBS833719
products full name :
CD258 antibody (PE)
products short name :
CD258
products name syn :
Monoclonal CD258; Anti-CD258; TR2; CD 258; CD-258; CD258; HVEml; TNFSF14; LTg
products gene name :
CD258
form :
Liquid containing 0.09% sodium azide. May contain carrier protein/stabilizer.
concentration :
200 ug/ml
storage stability :
Store at 4 degree C only. Do not freeze!
tested application :
Flow Cytometry (FC/FACS)
app notes :
FC: <= 1 ug/test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
other info1 :
Biological Significance: This 7-3 monoclonal antibody reacts with human CD258, a 29-kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-beta. Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator, LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-beta receptor.
other info2 :
Tag/Conjugate: PE
products categories :
Immunology; Conjugated Monoclonal Antibodies
products description :
Mouse monoclonal CD258 antibody (PE)