catalog number :
MBS833687
products full name :
C1 Esterase Inhibitor antibody (HRP)
products short name :
C1 Esterase Inhibitor
products name syn :
Polyclonal C1 Esterase Inhibitor; Anti-C1 Esterase Inhibitor; C1 Esterase Inhibitor; C Esterase Inhibitor 1; C Esterase Inhibitor-1
other names :
C4b-binding protein alpha chain; C4b-binding protein alpha chain; C4b-binding protein alpha chain; complement component 4 binding protein, alpha; Proline-rich protein; PRP
other gene names :
C4BPA; C4BPA; PRP; C4BP; C4BP; C4bp; PRP
uniprot entry name :
C4BPA_HUMAN
form :
Supplied in liquid form in a buffered stabilizer solution containing 50% (v/v) glycerol.
storage stability :
Store at -10 to -20 degree C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use.
tested application :
User optimized
other info1 :
Biological Significance: C1 Esterase Inhibitor is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement system to prevent spontaneous activation. C1-inhibitor is an acute-phase protein that circulates in blood at levels of around 0.25 g/L.
other info2 :
Tag/Conjugate: HRP. Immunogen: C1 Esterase Inhibitor antibody (HRP) was raised in goat using C1 esterase inhibitor purified from human plasma as the immunogen.
products categories :
Proteases, Inhibitors, Conjugated Polyclonal Antibodies
products description :
Goat polyclonal C1 Esterase Inhibitor antibody (HRP) conjugated
ncbi acc num :
NP_000706.1
ncbi gb acc num :
NM_000715.3
ncbi mol weight :
67,033 Da
ncbi pathways :
CD40/CD40L Signaling Pathway 138061!!Complement And Coagulation Cascades Pathway 83073!!Complement And Coagulation Cascades Pathway 484!!Complement Cascade Pathway 106405!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Pertussis Pathway 218111!!Pertussis Pathway 218099!!Regulation Of Complement Cascade Pathway 576254
ncbi summary :
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]