antibody

S100 antibody

MBS833662

0.25 ml

515 USD

polyclonal

rabbit

nonconjugated

Antibody

S100 antibody

S100

Polyclonal S100; Anti-S100; S-100; S 100; S100 Protein; S100 Astrocyte Marker; S100

S100 calcium binding protein B; Protein S100-B; protein S100-B; S100 calcium binding protein B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B

S100

S100B; S100B; NEF; S100; S100-B; S100beta

S100B_HUMAN

Polyclonal

Rabbit

To be determined by the end user

92

Bovine S100

Supplied in liquid form. Dilute immediately before use with PBS

Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

IHC: 1:50 - 1:100

Biological Significance: S-100 protein is a family of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix conformation. There are at least 21 different types of S100 proteins. which are involved in regulation of protein phosphorylation, transcription factors, Ca++ homeostasis, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.

Immunogen: S100 antibody was raised in rabbit using S-100 protein from bovine brain as the immunogen.

Cancer

Rabbit polyclonal S100 antibody

12804681

AAH01766.1

P04271

10,713 Da

Activated TLR4 Signalling Pathway 106400!!Advanced Glycosylation Endproduct Receptor Signaling Pathway 187092!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!DEx/H-box Helicases Activate Type I IFN And Inflammatory Cytokines Production Pathway 833822!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!MyD88 Cascade Initiated On Plasma Membrane Pathway 205107!!MyD88 Dependent Cascade Initiated On Endosome Pathway 187081!!MyD88-independent TLR3/TLR4 Cascade Pathway 106401!!MyD88:Mal Cascade Initiated On Plasma Membrane Pathway 106390

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]

0.25 ml

515 USD