catalog number :
MBS833529
products full name :
CITED4 antibody
products short name :
[CITED4]
products name syn :
[Polyclonal CITED4; Anti-CITED4; CITED-4; CITED 4; CITED4]
other names :
[cbp/p300-interacting transactivator 4; Cbp/p300-interacting transactivator 4; cbp/p300-interacting transactivator 4; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4; MSG1-related protein 2; MRG-2]
products gene name :
[CITED4]
other gene names :
[Cited4; Cited4; Mrg2; MRG-2; MRG-2]
uniprot entry name :
CITE4_MOUSE
form :
Lyophilized powder. Reconstitute with 100 ul of distilled water for a final concentration of 1.0 mg/ml in PBS with 2% Sucrose.
storage stability :
Ships ambient or refrigerated. Upon receipt store at 4°C for short term, -20°C for long term. Avoid repeat freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1.25 ug/ml
image1 heading :
Western Blot
other info1 :
Biological Significance: Cited4 is a member of The CITED family proteins that bind to CBP/p300 transcriptional integrators through their conserved C-terminal acidic domain and function as coactivators. It also interacts with isoforms of the TFAP2 transcription factor, coactivating TFAP2-dependent transcription.
other info2 :
Immunogen: Synthetic peptide directed toward the N-terminal region of mouse CITED4
products categories :
Signal Transduction
products description :
Rabbit polyclonal CITED4 antibody
ncbi gb acc num :
NM_019563.2
uniprot summary :
CITED4: Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells. Belongs to the CITED family. Cellular Component: cytoplasm; nucleus. Molecular Function: transcription coactivator activity. Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; response to estrogen stimulus; positive regulation of transcription, DNA-dependent