catalog number :
MBS832915
products full name :
CD41 antibody (PE)
products short name :
[CD41]
products name syn :
[Monoclonal CD41; Anti-CD41; CD-41; CD41; ITGA2b; CD 41; fibrinogen receptor; gpIIb/IIIa]
other names :
[CD41 antigen, partial; CD41 antigen; CD41 antigen]
products gene name :
[CD41]
other gene names :
[CD41]
uniprot entry name :
F7J059_TURTR
reactivity :
Not determined
form :
Liquid with 0.09% sodium azide. May contain carrier protein/stabilizer.
concentration :
0.2 mg/ml
storage stability :
Store at 4°C only.
tested application :
Flow Cytometry (FC/FACS)
app notes :
FC: 5 ul (0.25 ug)/test. A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
image1 heading :
Flow Cytometry (FC/FACS)
other info1 :
Biological Significance: The MWReg30 monoclonal antibody reacts with mouse CD41. While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also expressed on hematopoietic progenitors in the embryo, fetus and adult. CD41 associates with CD61 to form a receptor which plays a major role in platelet function, including binding of several adhesion molecules such as fibrinogen, fibronectin and vitronectin.Recently, the SLAM-family markers, CD48 and CD150 have been used to reliably identify hematopoietic stem cells. Specifically, it was found that CD150+CD48- bone marrow cells were highly efficient in their ability to confer long-term multi-lineage reconstitution in irradiated mice. Furthermore, the efficiency of reconstitution was enhanced when HSCs were further enriched through the exclusion of CD41+ cells. Thus, the use of CD150+CD48-CD41- as an expression profile efficiently identifies hematopoietic stem cells.
other info2 :
Tag/Conjugate: PE
products categories :
Immunology; Conjugated Monoclonal Antibodies
products description :
Rat monoclonal CD41 antibody (PE)
ncbi acc num :
BAK39702.1
ncbi mol weight :
20,050 Da