product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
SMAD1/5 antibody
catalog :
MBS832884
quantity :
0.1 mL
price :
375 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[AF10B7]
reactivity :
Saccoglossus kowalevskii
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
product information
catalog number :
MBS832884
products type :
Antibody
products full name :
SMAD1/5 antibody
products short name :
[SMAD1/5]
products name syn :
[Monoclonal SMAD1/5; Anti-SMAD1/5; SMAD1; SMAD family member 1; BMP pathway effector; BMP signal transducer SMAD1; BOS_16283; BSP1; BSP-1; dwarfin-A; dwf-A; EGK_16135; fb39h09; hypothetical protein; jv41; JV4-1; madh1; MAD homolog 1; MAD homolog 1 (Drosophila); MAD homolog1 (mothers against decapentaplegic; Drosophila); MAD (mothers against decapentaplegic; Drosophila) homolog 1; MAD; mothers against decapentaplegic homolog 1; Madr1; mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic-like protein 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; MusMLP; SMA- and MAD-related protein 1; SMAD-1; SMAD 1; SMAD; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; transforming growth factor-beta-signaling protein 1; Xmad1; XSMAD1]
other names :
[Smad1/5 protein; Smad1/5 protein]
products gene name :
[SMAD1/5]
other gene names :
[smad1/5]
clonality :
Monoclonal
isotype :
IgG2a/k
clone :
[AF10B7]
host :
Mouse
reactivity :
Human, Mouse, Rat
form :
Protein G purified liquid in HEPES with 0.15M NaCl, 0.01% BSA, 0.03% Sodium Azide, and 50% Glycerol
concentration :
1.0mg/ml
storage stability :
4°C short term; -20°C long term
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Usage recommendations: WB: 1:1000-2000
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: Recombinant human protein purified from E. coli
products categories :
Signal Transduction
products description :
In mammals, eight SMAD proteins have been identified to date. The SMAD family of proteins can be divided into three functional groups: the receptor-activated SMADs (R-SMADs), common mediator SMADs (Co-SMADs), and the inhibitory SMADs (I-SMADs). The R-SMADs are directly phosphorylated by the activated type I receptors on their C-terminal Ser-Ser-X-Ser (SSXS) motif and include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. SMAD2 and SMAD3 are phosphorylated in response to TGF-beta and activin, whereas SMAD1, SMAD5, and SMAD8 are phosphorylated in response to BMP (Bone Morphogenetic Protein). This C-terminal phosphorylation allows R-SMAD binding to Co-SMAD, SMAD4, and translocation to the nucleus where they regulate TGF-beta target genes. SMAD6 and SMAD7 belong to the I-SMAD which bind to the type I receptor or SMAD4 and block their interaction with R-SMADs.
ncbi gi num :
259013309
ncbi acc num :
NP_001158448.1
ncbi gb acc num :
NM_001164976.1
size1 :
0.1 mL
price1 :
375 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!