catalog number :
MBS832731
products full name :
OB Cadherin antibody
products short name :
OB Cadherin
products name syn :
Monoclonal OB Cadherin; Anti-OB Cadherin; CDH11; CAD11; CDHOB; OB; OSF-4; OB Cadherin
specificity :
Recognizes the extracellular domain of cadherin-11
form :
Supplied in PBS containing 0.09% sodium azide
tested application :
Immunohistochemistry (IHC), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
app notes :
IHC: 1:25-1:100. WB: 1:25-1:250
other info1 :
Biological Significance: OB Cadherin is a protein that in humans is encoded by the CDH11 gene. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
other info2 :
Immunogen: OB Cadherin antibody was raised in Mouse using affinity purified extracellular domain of human cadherin-11-GST fusion protein as the immunogen.
products categories :
Differentiation & Development
products description :
Mouse monoclonal OB Cadherin antibody