catalog number :
MBS832358
products full name :
Heat Stable Enterotoxin antibody
products short name :
Heat Stable Enterotoxin
products name syn :
Monoclonal Heat Stable Enterotoxin; Anti-Heat Stable Enterotoxin; Enterotoxin
other names :
heat stable enterotoxin, partial; Heat stable enterotoxin; Heat stable enterotoxin
uniprot entry name :
Q6BCH1_EDWIC
specificity :
Specific to Heat-stable enterotoxin (STp)
purity :
> 95% pure. Heat Stable Enterotoxin antibody was purified by Protein A or G affinity purification
form :
Supplied as a liquid in PBS, pH 7.4, 3mM KCl, 1.5mM KH2PO4, 140mM NaCl, 8.0mM Na2HPO4
concentration :
1-3 mg/ml
storage stability :
Store at 4 degree C for short term or -20 degree C for longer storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA)
app notes :
MBS832358 can be used as the capture antibody with MBS834216 as the detection antibody in ELISA. Another excellent pairing is MBS834211 as the capture antibody and MBS832358 as the detection antibody
other info1 :
Biological Significance: Heat-stable enterotoxins (STs) are secretory peptides produced by some bacterial strains, such as enterotoxigenic Escherichia coli which are in general toxic to animals. These peptides keep their 3D structure and remain active at temperatures as high as 100 deg C. Different STs recognize distinct receptors on the surface of animal cells and thereby affect different intracellular signaling pathways. For example, STa enterotoxins bind and activate membrane-bound guanylate cyclase, which leads to the intracellular accumulation of cyclic GMP and downstream effects on several signaling pathways. These events lead to the loss of electrolytes and water from intestinal cells.
other info2 :
Biohazard Information: This product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: Heat Stable Enterotoxin antibody was raised in mouse using STp peptide (18 amino acid length) coupled with KLH to the N terminal or C terminal, respectively as the immunogen.
products categories :
Infectious Disease
products description :
Mouse monoclonal Heat Stable Enterotoxin Monoclonal antibody
ncbi acc num :
AAT77724.1
ncbi mol weight :
3,684 Da