product summary
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company name :
MyBioSource
product type :
antibody
product name :
V alpha 24 J alpha 18 TCR antibody (PE)
catalog :
MBS832325
quantity :
100 Tests
price :
615 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
6B11
application :
flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS832325
products type :
Antibody
products full name :
V alpha 24 J alpha 18 TCR antibody (PE)
products short name :
V alpha 24 J alpha 18 TCR
products name syn :
Monoclonal V alpha 24 J alpha 18 TCR; Anti-V alpha 24 J alpha 18 TCR; V alpha 24 J alpha18; V alpha 24 J alpha 18; V alpha 24 J alpha 18 TCR; V alpha J alpha 18 TCR 24; Va24-Ja18 TCR; V alpha J alpha 18 TCR-24
clonality :
Monoclonal
isotype :
IgG1 kappa
clone :
6B11
host :
Mouse
specificity :
Mouse
form :
Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
concentration :
200 ug/ml
storage stability :
Store at 2-8 degree C. Do not freeze. Protect from light.
tested application :
Flow Cytometry (FC/FACS)
app notes :
This can be used at the same concentration as the experimental antibody
other info1 :
Biological Significance: The 6B11 monoclonal antibody reacts with an epitope of the CDR3 formed by the germ-line configuration of the V alpha 24 and J alpha18 of the TCR alpha locus, which results in the expression of an invariant T-cell receptor expressed by invariant NK T cells. This TCR is homologous to the murine V alpha14J alpha18. This TCR alpha chain pairs with a restricted set of rearranged TCR beta chains, with V beta11 being the most prominent in humans. NK T cells are restricted by the CD1d molecule and are activated by a CD1d-presented glycolipid ligand, which results in the rapid production of IL-4, IL-13 and IFNgamma. Although iNKT cells have NK-like cytolytic activity, they are considered regulators of immune responses because they rapidly produce large amounts of both Th1 and Th2 cytokines in autoimmune disease, infectious disease, and cancer. The number of iNKT cells present in peripheral blood of normal humans shows considerable variability ranging from 0.01-1% of total peripheral T cells.
other info2 :
Tag/Conjugate: PE
products categories :
Signal Transduction; Conjugated Monoclonal Antibodies
products description :
Mouse monoclonal V alpha 24 J alpha 18 TCR antibody (PE)
size :
100 Tests
price :
615 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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