catalog number :
MBS831464
products full name :
HER2 antibody
products short name :
HER2
products name syn :
Monoclonal HER2; Anti-HER2; HER-2; HER 2; HER2
other names :
hairy-related 2; HER-2 protein; hairy-related 2; hairy-related 2; HER-2 protein
products gene name :
HER2
other gene names :
her2; her2; HER-2
uniprot entry name :
Q90464_DANRE
form :
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
ELISA: 1:10,000. IHC: 1:200-1:1000. WB: 1:500-1:2000
other info1 :
Biological Significance: HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. It is encoded within the genome by HER2/neu, a known proto-oncogene. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. However, ErbB receptors dimerise on ligand binding, and HER2 is the preferential dimerisation partner of other members of the ErbB family.
other info2 :
Immunogen: HER2 antibody was raised in Mouse using a purified recombinant fragment of HER-2 expressed in E Coli as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal HER2 antibody
ncbi acc num :
NP_571164.1
ncbi gb acc num :
NM_131089.1
ncbi mol weight :
12,416 Da