antibody

Lysozyme antibody

MBS831377

5 mL

230 USD

monoclonal

mouse

nonconjugated

LYZ-Z

western blot, immunohistochemistry

Antibody

Lysozyme antibody

Lysozyme

Monoclonal Lysozyme; Anti-Lysozyme; Lyz; 1 4 beta n acetylmuramidase c; Lysozyme C; LZM; EC 3.2.1.17; lysosyme; Lysozyme; Anti Lysozyme; Lysozyme C precursor

lysozyme (EC 3.2.1.17); Lysozyme C; lysozyme C; lysozyme; 1,4-beta-N-acetylmuramidase C

LYZ; LYZ; LZM; LZM

LYSC_HUMAN

Monoclonal

IgG1 kappa

LYZ-Z

Mouse

Frog, Fish

148

Human Lysozyme

Supplied in liquid form, contains 0.09% NaN3

5.0 ml

Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC), Western Blot (WB)

Biological Significance: Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, are glycoside hydrolases, enzymes that damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Immunogen: Lysozyme antibody was raised in mouse using human lysozyme as the immunogen.

Proteases, Inhibitors, & Enzymes

Mouse monoclonal Lysozyme antibody

307142

AAA59536.1

P61626

16,537 Da

Amyloids Pathway (366238); C-MYB Transcription Factor Network Pathway (138073); Disease Pathway (530764); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352)

This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]

LYZ: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents. Defects in LYZ are a cause of amyloidosis type 8 (AMYL8); also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash. Belongs to the glycosyl hydrolase 22 family. Protein type: Secreted; Endoplasmic reticulum; Hydrolase; Vesicle; Secreted, signal peptide; EC 3.2.1.17. Chromosomal Location of Human Ortholog: 12q15. Cellular Component: extracellular space; extracellular region. Molecular Function: identical protein binding; lysozyme activity. Biological Process: retinal homeostasis; metabolic process; cytolysis; defense response to bacterium; inflammatory response. Disease: Amyloidosis, Familial Visceral

5 mL

230 USD