This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
alpha beta Synuclein antibody
catalog :
MBS830962
quantity :
0.1 ml
price :
360 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3B6
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
product information
catalog number :
MBS830962
products type :
Antibody
products full name :
alpha beta Synuclein antibody
products short name :
alpha beta Synuclein
products name syn :
Monoclonal alpha beta Synuclein; Anti-alpha; Non A beta component of AD amyloid; Synuclein beta; beta-Synuclein; NACP; beta synuclein; PARK1; SNCB protein; Parkinson disease familial 1; alpha synuclein; SNCA; b synuclein; Non A4 component of amyloid precursor; PD1; a; Synuclein alpha; SNCB; PARK4
other names :
alpha-synuclein isoform NACP140; Alpha-synuclein; alpha-synuclein; synuclein, alpha (non A4 component of amyloid precursor); Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
other gene names :
SNCA; SNCA; PD1; NACP; PARK1; PARK4; NACP; PARK1; NACP
uniprot entry name :
SYUA_HUMAN
clonality :
Monoclonal
isotype :
IgG1 kappa
clone :
3B6
host :
Mouse
reactivity :
Human, Mouse, Rat
sequence length :
140
specificity :
Human
purity :
alpha, beta Synuclein antibody was purified by protein-G affinity chromatography
form :
Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
concentration :
1 mg/ml
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:1000-1:2,000
other info1 :
Biological Significance: Anti-human alpha, beta-synuclein antibody, clone 3B6, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human beta-synuclein protein. alpha-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.
other info2 :
Immunogen: alpha, beta Synuclein antibody was raised in mouse using recombinant human a-synuclein (119-140aa) purified from E Coli as the immunogen.
products categories :
Neuroscience
products description :
Mouse monoclonal alpha, beta Synuclein antibody
ncbi gi num :
4507109
ncbi acc num :
NP_000336.1
ncbi gb acc num :
NM_000345.3
uniprot acc num :
P37840
ncbi mol weight :
13,109 Da
ncbi pathways :
Alpha-synuclein Signaling Pathway 137913!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Amyloids Pathway 366238!!Disease Pathway 530764!!EGFR1 Signaling Pathway 198782!!Parkin-Ubiquitin Proteasomal System Pathway 700638!!Parkinson's Disease Pathway 83098!!Parkinsons Disease Pathway 705377
ncbi summary :
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
size :
0.1 ml
price :
360 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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