product summary
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company name :
MyBioSource
product type :
antibody
product name :
Nucleophosmin antibody
catalog :
MBS830822
quantity :
0.1 ml
price :
335 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7H10B9
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS830822
products type :
Antibody
products full name :
Nucleophosmin antibody
products short name :
Nucleophosmin
products name syn :
Monoclonal Nucleophosmin; Anti-Nucleophosmin; MGC104254; nucleolar phosphoprotein B23; NPM; nucleophosmin/nucleoplasmin family; Nucleophosmin; numatrin; B23; Anti Nucleophosmin; member 1; Nucleolar phosphoprotein B23
other names :
nucleophosmin; Nucleophosmin; nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
other gene names :
NPM1; NPM1; B23; NPM; NPM; NPM
uniprot entry name :
NPM_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
7H10B9
host :
Mouse
reactivity :
Human, Monkey
sequence length :
294
form :
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
ELISA: 1:10,000. IF: 1:200-1:1000. IHC: 1:200-1:1000. WB: 1:500-1:2000
other info1 :
Biological Significance: Nucleophosmin is a nucleolar phosphoprotein that binds the tumor suppressors p53 and p19Arf and is thought to be indispensable for ribogenesis, cell proliferation, and survival after DNA damage. Nucleophosmin is upregulated in many cancer cells.
other info2 :
Immunogen: Nucleophosmin antibody was raised in Mouse using a purified recombinant fragment of human NPM expressed in E Coli as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal Nucleophosmin antibody
ncbi gi num :
189272
ncbi acc num :
AAA36380.1
uniprot acc num :
P06748
ncbi mol weight :
28,400 Da
ncbi pathways :
Aurora B Signaling Pathway 138080!!BARD1 Signaling Events Pathway 137959!!Cell Cycle Pathway 530733!!Chromosome Maintenance Pathway 161048!!Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway 161050!!Disease Pathway 530764!!HIF-1-alpha Transcription Factor Network Pathway 138045!!HIV Infection Pathway 105983!!Host Interactions Of HIV Factors Pathway 106010!!Infectious Disease Pathway 1183535
ncbi summary :
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
size :
0.1 ml
price :
335 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

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