product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD19 antibody
catalog :
MBS830632
quantity :
0.1 ml
price :
385 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2.00E+02
reactivity :
human
application :
ELISA, flow cytometry, FACS
more info or order :
product information
catalog number :
MBS830632
products type :
Antibody
products full name :
CD19 antibody
products short name :
CD19
products name syn :
Monoclonal CD19; Anti-CD19; CD-19; CD 19; CD19; B-lymphocyte antigen CD19; Cluster of Differentiation 19
other names :
CD19, partial; CD19; B-lymphocyte antigen CD19; CD19 molecule; CD19
products gene name :
CD19
other gene names :
CD19; CD19; B4; CVID3
uniprot entry name :
Q71UW0_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2.00E+02
host :
Mouse
reactivity :
Human
sequence length :
92
form :
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA, Flow Cytometry (FC/FACS)
app notes :
ELISA: 1:10,000. FC: 1:200-1:400
other info1 :
Biological Significance: CD19 is a protein that in humans is encoded by the CD19 gene. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.
other info2 :
Immunogen: CD19 antibody was raised in Mouse using a purified recombinant fragment of human CD19 expressed in E Coli as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD19 antibody
ncbi gi num :
4105281
ncbi acc num :
AAD02340.1
uniprot acc num :
Q71UW0
ncbi mol weight :
10,185 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway 576249!!B Cell Receptor Signaling Pathway 198909!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!BCR Signaling Pathway 138058!!Constitutive Signaling By Aberrant PI3K In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764
ncbi summary :
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
size :
0.1 ml
price :
385 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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