catalog number :
MBS830477
products full name :
AFP antibody
products short name :
AFP
products name syn :
Monoclonal AFP; Anti-AFP; alpha-Fetoprotein; alpha Fetoprotein
other names :
alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
other gene names :
AFP; AFP; AFPD; FETA; HPAFP; HPAFP
uniprot entry name :
FETA_HUMAN
purity :
> 90% pure. AFP antibody was purified by Ion exchange chromatography.
form :
Supplied in PBS with 0.09% sodium azide as preservative
concentration :
17.6 mg/ml
storage stability :
Store at 4 degree C for short term storage. For long term storage, aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Lateral Flow
app notes :
Lateral Flow Pairs: MBS830477 can be used as the membrane coating antibody, with MBS830611 as the conjugate antibody
other info1 :
Biological Significance: Alpha-fetoprotein (AFP) is a protein that in humans is encoded by the AFP gene. Alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4.
other info2 :
Immunogen: AFP antibody was raised in mouse using Alpha-fetoprotein as the immunogen.
products categories :
Cancer
products description :
Mouse Monoclonal AFP antibody
ncbi acc num :
NP_001125.1
ncbi gb acc num :
NM_001134.1
ncbi mol weight :
68,678 Da
ncbi pathways :
Direct P53 Effectors Pathway 137939!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Hippo Signaling Pathway 749777!!Hippo Signaling Pathway 750388
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]