product summary
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company name :
MyBioSource
product type :
protein
product name :
Dectin 2 Blocking Peptide
catalog :
MBS829738
quantity :
1 mg
price :
160 USD
more info or order :
product information
catalog number :
MBS829738
products type :
Blocking Peptide
products full name :
Dectin 2 Blocking Peptide
products short name :
[Dectin 2]
products name syn :
[CLECSF10; DECTIN2; C-type lectin domain family 6 member A; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2; DC-associated C-type lectin 2; Dectin-2]
other names :
[C-type lectin domain family 6 member A; C-type lectin domain family 6 member A; C-type lectin domain family 6 member A; C-type lectin domain family 6, member A; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2; DC-associated C-type lectin 2; Dectin-2]
products gene name :
[CLEC6A]
other gene names :
[CLEC6A; CLEC6A; CLEC4N; CLECSF10; CLECSF10; DECTIN2; DC-associated C-type lectin 2; Dectin-2]
uniprot entry name :
CLC6A_HUMAN
host :
Synthetic
reactivity :
Human, Mouse, Rat
sequence length :
209
purity :
>85%
form :
Lyophilized powder
storage stability :
Ships on blue ice. Store at -20°C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4°C for overnight or at room temperature for 2 hours.
other info2 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-Dectin 2 Antibody reactivity.
ncbi gi num :
55742774
ncbi acc num :
NP_001007034.1
ncbi gb acc num :
NM_001007033.1
uniprot acc num :
Q6EIG7
ncbi pathways :
C-type Lectin Receptors (CLRs) Pathway (1269303); Dectin-2 Family Pathway (1269308); Immune System Pathway (1269170); Innate Immune System Pathway (1269203)
ncbi summary :
Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 [PubMed 15175046]).[supplied by OMIM, Nov 2010]
uniprot summary :
dectin-2: Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: integral to membrane. Molecular Function: carbohydrate binding. Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; defense response to fungus; positive regulation of cytokine secretion
size1 :
1 mg
price1 :
160 USD
size2 :
5 mg
price2 :
305
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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