catalog number :
MBS8292795
products full name :
Anti-SSH2 Antibody
products short name :
[SSH2]
products name syn :
[KIAA1725; SSH2L; Protein phosphatase Slingshot homolog 2; SSH-like protein 2; SSH-2L; hSSH-2L]
other names :
[protein phosphatase Slingshot homolog 2 isoform 1; Protein phosphatase Slingshot homolog 2; protein phosphatase Slingshot homolog 2; slingshot protein phosphatase 2; SSH-like protein 2; SSH-2L; hSSH-2L]
products gene name :
[SSH2]
other gene names :
[SSH2; SSH2; SSH-2; SSH-2L; KIAA1725; SSH2L; SSH-2L; hSSH-2L]
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of SSH2 protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1/500 - 1/2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant full length protein of human SSH2
products description :
Rabbit polyclonal antibody to SSH2
ncbi acc num :
NP_001269058.1
ncbi gb acc num :
NM_001282129.1
ncbi pathways :
Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Regulation Of Actin Cytoskeleton Pathway (198874); Regulation Of Actin Cytoskeleton Pathway (83089); Regulation Of Actin Cytoskeleton Pathway (500)
ncbi summary :
This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
uniprot summary :
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.