catalog number :
MBS8292763
products full name :
Anti-PB1 Antibody
products short name :
[PB1]
products name syn :
[BAF180; PB1; Protein polybromo-1; hPB1; BRG1-associated factor 180; BAF180; Polybromo-1D]
other names :
[protein polybromo-1 isoform 2; Protein polybromo-1; protein polybromo-1; polybromo 1; BRG1-associated factor 180; BAF180; Polybromo-1D]
products gene name :
[PB1]
products gene name syn :
[PBRM1]
other gene names :
[PBRM1; PBRM1; PB1; BAF180; BAF180; PB1; hPB1; BAF180]
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of PB1 protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1/500 - 1/2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant full length protein of human PB1
products description :
Rabbit polyclonal antibody to PB1
ncbi acc num :
NP_060783.3
ncbi gb acc num :
NM_018313.4
ncbi mol weight :
184,043 Da
ncbi summary :
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]
uniprot summary :
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation.