product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-ChREBP Antibody
catalog :
MBS8292496
quantity :
0.05 mL
price :
175 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8292496 image 1
Western blot analysis of ChREBP expression in HT29 (A), K562 (B), mouse liver (C), mouse kidney (D) whole cell lysates.
product information
catalog number :
MBS8292496
products type :
Antibody
products full name :
Anti-ChREBP Antibody
products short name :
[ChREBP]
products name syn :
[BHLHD14; MIO; WBSCR14; Carbohydrate-responsive element-binding protein; ChREBP; Class D basic helix-loop-helix protein 14; bHLHd14; MLX interactor; MLX-interacting protein-like; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH; Williams-Beuren syndrome chromosomal region 14 protein]
other names :
[carbohydrate-responsive element-binding protein isoform alpha; Carbohydrate-responsive element-binding protein; carbohydrate-responsive element-binding protein; MLX interacting protein like; Class D basic helix-loop-helix protein 14; bHLHd14; MLX interactor; MLX-interacting protein-like; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH; Williams-Beuren syndrome chromosomal region 14 protein]
products gene name :
[ChREBP]
products gene name syn :
[MLXIPL]
other gene names :
[MLXIPL; MLXIPL; MIO; MLX; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14; BHLHD14; MIO; WBSCR14; ChREBP; bHLHd14; WS-bHLH]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
722
specificity :
Recognizes endogenous levels of ChREBP protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunoprecipitation (IP)
app notes :
WB: 1/500 - 1/2000. IP: 1/50 - 1/100
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant full length protein of human ChREBP
products description :
Rabbit polyclonal antibody to ChREBP
ncbi gi num :
14602433
ncbi acc num :
NP_116569.1
ncbi gb acc num :
NM_032951.2
uniprot acc num :
Q9NP71
ncbi pathways :
AMPK Inhibits ChREBP Transcriptional Activation Activity Pathway (1270112); ChREBP Activates Metabolic Gene Expression Pathway (1270114); Insulin Resistance Pathway (1272486); Integration Of Energy Metabolism Pathway (1270101); Metabolism Pathway (1269956); Non-alcoholic Fatty Liver Disease (NAFLD) Pathway (862188); Non-alcoholic Fatty Liver Disease (NAFLD) Pathway (862314); PKA-mediated Phosphorylation Of Key Metabolic Factors Pathway (1270110); PP2A-mediated Dephosphorylation Of Key Metabolic Factors Pathway (1270113)
ncbi summary :
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
uniprot summary :
Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' ().
size1 :
0.05 mL
price1 :
175 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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