catalog number :
MBS8292430
products full name :
Anti-TMLHE Antibody
products short name :
[TMLHE]
products name syn :
[TMLH; Trimethyllysine dioxygenase, mitochondrial; Epsilon-trimethyllysine 2-oxoglutarate dioxygenase; Epsilon-trimethyllysine hydroxylase; TML hydroxylase; TML-alpha-ketoglutarate dioxygenase; TML dioxygenase; TMLD]
other names :
[trimethyllysine dioxygenase, mitochondrial isoform 2; Trimethyllysine dioxygenase, mitochondrial; trimethyllysine dioxygenase, mitochondrial; trimethyllysine hydroxylase, epsilon; Epsilon-trimethyllysine 2-oxoglutarate dioxygenase; Epsilon-trimethyllysine hydroxylase; TML hydroxylase; TML-alpha-ketoglutarate dioxygenase; TML dioxygenase; TMLD]
products gene name :
[TMLHE]
other gene names :
[TMLHE; TMLHE; TMLD; TMLH; BBOX2; AUTSX6; TMLHED; XAP130; TMLH; TML dioxygenase; TMLD]
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of TMLHE protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipping: Blue ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
WB: 1/500 - 1/2000. IF/ICC: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant full length protein of human TMLHE
products description :
Rabbit polyclonal antibody to TMLHE
ncbi acc num :
NP_001171726.1
ncbi gb acc num :
NM_001184797.1
ncbi pathways :
Carnitine Synthesis Pathway (106191); L-carnitine Biosynthesis Pathway (545318); Lysine Degradation Pathway (82956); Lysine Degradation Pathway (320); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169)
ncbi summary :
This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
uniprot summary :
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML) (PubMed:11431483, PubMed:23092983).