product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-TMLHE Antibody
catalog :
MBS8292430
quantity :
0.05 mL
price :
175 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
image
image 1 :
MyBioSource MBS8292430 image 1
Western blot analysis of TMLHE expression in HT29 (A), SKOV3 (B), mouse heart (C), rat liver (D) whole cell lysates.
image 2 :
MyBioSource MBS8292430 image 2
Immunofluorescent analysis of TMLHE staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
product information
catalog number :
MBS8292430
products type :
Antibody
products full name :
Anti-TMLHE Antibody
products short name :
[TMLHE]
products name syn :
[TMLH; Trimethyllysine dioxygenase, mitochondrial; Epsilon-trimethyllysine 2-oxoglutarate dioxygenase; Epsilon-trimethyllysine hydroxylase; TML hydroxylase; TML-alpha-ketoglutarate dioxygenase; TML dioxygenase; TMLD]
other names :
[trimethyllysine dioxygenase, mitochondrial isoform 2; Trimethyllysine dioxygenase, mitochondrial; trimethyllysine dioxygenase, mitochondrial; trimethyllysine hydroxylase, epsilon; Epsilon-trimethyllysine 2-oxoglutarate dioxygenase; Epsilon-trimethyllysine hydroxylase; TML hydroxylase; TML-alpha-ketoglutarate dioxygenase; TML dioxygenase; TMLD]
products gene name :
[TMLHE]
other gene names :
[TMLHE; TMLHE; TMLD; TMLH; BBOX2; AUTSX6; TMLHED; XAP130; TMLH; TML dioxygenase; TMLD]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
432
specificity :
Recognizes endogenous levels of TMLHE protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipping: Blue ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
WB: 1/500 - 1/2000. IF/ICC: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant full length protein of human TMLHE
products description :
Rabbit polyclonal antibody to TMLHE
ncbi gi num :
296317249
ncbi acc num :
NP_001171726.1
ncbi gb acc num :
NM_001184797.1
uniprot acc num :
Q9NVH6
ncbi pathways :
Carnitine Synthesis Pathway (106191); L-carnitine Biosynthesis Pathway (545318); Lysine Degradation Pathway (82956); Lysine Degradation Pathway (320); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169)
ncbi summary :
This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
uniprot summary :
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML) (PubMed:11431483, PubMed:23092983).
size1 :
0.05 mL
price1 :
175 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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