catalog number :
MBS8292351
products full name :
Anti-CAC Antibody
products short name :
[CAC]
products name syn :
[CAC; CACT; Mitochondrial carnitine/acylcarnitine carrier protein; Carnitine/acylcarnitine translocase; CAC; Solute carrier family 25 member 20]
other names :
[mitochondrial carnitine/acylcarnitine carrier protein; Mitochondrial carnitine/acylcarnitine carrier protein; mitochondrial carnitine/acylcarnitine carrier protein; solute carrier family 25 member 20; Carnitine/acylcarnitine translocase; CAC; Solute carrier family 25 member 20]
products gene name :
[CAC]
products gene name syn :
[SLC25A20]
other gene names :
[SLC25A20; SLC25A20; CAC; CACT; CAC; CACT; CAC]
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of CAC protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Ships on blue ice. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
WB: 1/500 - 1/2000. IF/ICC: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant full length protein of human CAC
products description :
Rabbit polyclonal antibody to CAC
ncbi acc num :
NP_000378.1
ncbi gb acc num :
NM_000387.5
ncbi pathways :
Fatty Acid Beta Oxidation Pathway (198865); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway (106108); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Mitochondrial LC-Fatty Acid Beta-Oxidation Pathway (198817)
ncbi summary :
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]
uniprot summary :
Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.