catalog number :
MBS8292020
products full name :
Anti-INPP5A Antibody
products short name :
[INPP5A]
products name syn :
[Type I inositol 1,4,5-trisphosphate 5-phosphatase; 5PTase]
other names :
[type I inositol 1,4,5-trisphosphate 5-phosphatase isoform b; Type I inositol 1,4,5-trisphosphate 5-phosphatase; type I inositol 1,4,5-trisphosphate 5-phosphatase; inositol polyphosphate-5-phosphatase A]
products gene name :
[INPP5A]
other gene names :
[INPP5A; INPP5A; 5PTASE; 5PTase]
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of INPP5A protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Ships on blue ice. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1/500 - 1/2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant full length protein of human INPP5A
products description :
Rabbit polyclonal antibody to INPP5A
ncbi acc num :
NP_001307971.1
ncbi gb acc num :
NM_001321042.1
ncbi pathways :
1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway (545332); 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway (138949); D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway (545328); D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway (138943); D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway (545327); D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway (138942); Inositol Phosphate Metabolism Pathway (82987); Inositol Phosphate Metabolism Pathway (1269988); Inositol Phosphate Metabolism Pathway (362); Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 = Ins(1,3,4)P3 = Myo-inositol Pathway (413401)
ncbi summary :
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]
uniprot summary :
Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.