antibody

Anti-LAT1 Antibody

MBS8291984

0.05 mL

175 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

Antibody

Anti-LAT1 Antibody

[LAT1]

[CD98LC; LAT1; MPE16; Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter]

[large neutral amino acids transporter small subunit 1; Large neutral amino acids transporter small subunit 1; large neutral amino acids transporter small subunit 1; solute carrier family 7 member 5; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter]

[LAT1]

[SLC7A5]

[SLC7A5; SLC7A5; E16; CD98; LAT1; 4F2LC; MPE16; D16S469E; CD98LC; LAT1; MPE16; 4F2 LC; 4F2LC; hLAT1]

Polyclonal

Rabbit

Human, Mouse, Rat

507

Recognizes endogenous levels of LAT1 protein.

Purified by immunogen affinity chromatography

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Ships on blue ice. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

WB: 1/500 - 1/2000

Western Blot (WB)

Immunogen: Recombinant full length protein of human LAT1

Rabbit polyclonal antibody to LAT1

71979932

NP_003477.4

NM_003486.6

Q01650

Amino Acid Transport Across The Plasma Membrane Pathway (106170); Basigin Interactions Pathway (106065); Cell Surface Interactions At The Vascular Wall Pathway (106062); Hemostasis Pathway (106028); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway (119559)

Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts. When associated with LAPTM4B, recruits SLC3A2 and SLC7A5 to lysosomes to promote leucine uptake into these organelles and is required for mTORC1 activation (PubMed:25998567).

0.05 mL

175 USD

0.1 mL

220

0.2 mL

295