catalog number :
MBS8291882
products full name :
Anti-Surfactant Protein C Antibody
products short name :
[Surfactant Protein C]
products name syn :
[SFTP2; Pulmonary surfactant-associated protein C; SP-C; Pulmonary surfactant-associated proteolipid SPL(Val); SP5]
other names :
[pulmonary surfactant-associated protein C isoform 2; Pulmonary surfactant-associated protein C; pulmonary surfactant-associated protein C; surfactant protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SP5]
products gene name :
[SFTPC]
other gene names :
[SFTPC; SFTPC; SP-C; PSP-C; SFTP2; SMDP2; BRICD6; SFTP2; SP-C]
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of Surfactant Protein C protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipping: Blue ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
WB: 1/500 - 1/2000. IHC: 1/50 - 1/200. IF/ICC: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant full length protein of human Surfactant Protein C
products description :
Rabbit polyclonal antibody to Surfactant Protein C
ncbi acc num :
NP_001165828.1
ncbi gb acc num :
NM_001172357.1
ncbi summary :
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
uniprot summary :
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.