catalog number :
MBS8291594
products full name :
Anti-ENT3 Antibody
products short name :
[ENT3]
products name syn :
[ENT3; Equilibrative nucleoside transporter 3; hENT3; Solute carrier family 29 member 3]
other names :
[equilibrative nucleoside transporter 3 isoform b; Equilibrative nucleoside transporter 3; equilibrative nucleoside transporter 3; solute carrier family 29 member 3; Solute carrier family 29 member 3]
products gene name :
[ENT3]
products gene name syn :
[SLC29A3]
other gene names :
[SLC29A3; SLC29A3; ENT3; HJCD; PHID; HCLAP; ENT3; hENT3]
specificity :
Recognizes endogenous levels of ENT3 protein.
purity :
Purified by immunogen affinity chromatography
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipping: Blue Ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1/500 - 1/2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant full length protein of human ENT3
products description :
Rabbit polyclonal antibody to ENT3
ncbi acc num :
NP_001167569.1
ncbi gb acc num :
NM_001174098.1
ncbi pathways :
SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Nucleosides And Free Purine And Pyrimidine Bases Across The Plasma Membrane Pathway (106264); Transport Of Vitamins, Nucleosides, And Related Molecules Pathway (161075)
ncbi summary :
This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010]
uniprot summary :
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine.