catalog number :
MBS824972
products type :
ELISA Kit
products full name :
Mouse CXCL2 ELISA Kit
products short name :
[CXCL2]
products name syn :
[GRO2; GROB; MIP2A; SCYB2; C-X-C motif chemokine 2; Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha]
other names :
[C-X-C motif chemokine 2; C-X-C motif chemokine 2; C-X-C motif chemokine 2; macrophage inflammatory protein 2; small inducible cytokine subfamily, member 2; chemokine (C-X-C motif) ligand 2; Macrophage inflammatory protein 2; MIP2]
products gene name :
[CXCL2]
other gene names :
[Cxcl2; Cxcl2; GROb; Gro2; Mip2; Scyb; MIP-2; Scyb2; MIP-2a; Mgsa-b; CINC-2a; Mip-2; Mip2; Scyb2; MIP2]
uniprot entry name :
CXCL2_MOUSE
specificity :
The Mouse CXCL2 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse CXCL2 proteins within the range of 15.6 pg/ml - 1000 pg/ml.
storage stability :
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Sandwich ELISA (SE)
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Cell Culture Supernatants, Serum, Plasma. Sensitivity: 7 pg/ml.
products description :
Principle of the Assay: The Mouse CXCL2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse CXCL2 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Mouse CXCL2 coated on a 96-well plate. Standards and samples are pipetted into the wells and CXCL2 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse CXCL2 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CXCL2 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: MIP is a member of the aquaporin family of membrane-bound water channels. MIP family proteins are thought to contain 6 TM domains. Sequence analysis suggests that the proteins may have arisen through tandem, intragenic duplication from an ancestral protein that contained 3 TM domains. Major intrinsic protein (MIP, also called MP26) is the predominant fiber cell membrane protein of the ocular lens. The major intrinsic protein (MIP) of the vertebrate eye lens is the first identified member of a sequence-related family of cell-membrane proteins that appears to have evolved by gene duplication. Several members of the MIP family transport water (aquaporins), glycerol and other small molecules in microbial, plant and animal cells.
ncbi acc num :
NP_033166.1
ncbi gb acc num :
NM_009140.2
ncbi mol weight :
10,621 Da
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (1000944); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1000942); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); G Alpha (i) Signalling Events Pathway (1000973); GPCR Downstream Signaling Pathway (1000971); GPCR Ligand Binding Pathway (1000941)
uniprot summary :
Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst.