Recombinant Mouse IL18 Protein | MyBioSource MBS8249249 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Mouse IL18 Protein

catalog :

MBS8249249

quantity :

0.01 mg

price :

205 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS8249249

products type :

Recombinant Protein

products full name :

Recombinant Mouse IL18 Protein

products short name :

[IL18]

products name syn :

[IGIF; IL1F4; Interleukin-18; IL-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma]

other names :

[interleukin-18; Interleukin-18; interleukin-18; interleukin 18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma]

products gene name :

[IL18]

other gene names :

[Il18; Il18; Igif; Il-18; Igif; IL-18; IFN-gamma-inducing factor; IL-1 gamma]

uniprot entry name :

IL18_MOUSE

reactivity :

Mouse

sequence length :

192

sequence :

MNHKVHHHHH HMNFGRLHCT TAVIRNINDQ VLFVDKRQPV FEDMTDIDQS ASEPQTRLII YMYKDSEVRG LAVTLSVKDS KMSTLSCKNK IISFEEMDPP ENIDDIQSDL IFFQKRVPGH NKMEFESSLY EGHFLACQKE DDAFKLILKK KDENGDKSVM FTLTNLHQS

purity :

Greater than 95% as determined by reducing SDS-PAGE.

form :

Lyophilized from a 0.2 uM filtered solution of PBS, pH 7.4.

storage stability :

Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.

tested application :

E, WB, SDS=PAGE, MS

other info1 :

. Source: E.Coli. Quality Control: Endotoxin: Less than 0.1 Ug/Ug (1 IEU/Ug) as determined by LAL test.

other info2 :

Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

products description :

Recombinant Mouse IL18 Protein is produced by our E. coli expression system and the target gene encoding Asn36-Ser192 is expressed with a 6His tag at the N-terminus.

ncbi gi num :

6680413

ncbi acc num :

NP_032386.1

ncbi gb acc num :

NM_008360.1

uniprot acc num :

P70380

ncbi pathways :

African Trypanosomiasis Pathway (194387); African Trypanosomiasis Pathway (194323); Cytokine Signaling In Immune System Pathway (1367586); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125146); Cytosolic DNA-sensing Pathway (124833); Hypertrophy Model Pathway (198326); Immune System Pathway (1367472); Inflammatory Bowel Disease (IBD) Pathway (842778)

uniprot summary :

IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family. Protein type: Cytokine. Cellular Component: apical plasma membrane; cytoplasm; extracellular space. Molecular Function: cytokine activity. Biological Process: activation of protein kinase B; angiogenesis; cholesterol homeostasis; detection of mechanical stimulus involved in sensory perception of pain; immune response; induction of apoptosis via death domain receptors; inflammatory response; interferon-gamma biosynthetic process; interleukin-13 biosynthetic process; lipopolysaccharide-mediated signaling pathway; MAPKKK cascade; natural killer cell activation; negative regulation of myoblast differentiation; negative regulation of neutrophil apoptosis; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of activated T cell proliferation; positive regulation of apoptosis; positive regulation of chemokine production; positive regulation of collagen biosynthetic process; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of interferon-gamma production; positive regulation of interleukin-17 production; positive regulation of interleukin-8 production; positive regulation of natural killer cell proliferation; positive regulation of neuron apoptosis; positive regulation of NF-kappaB import into nucleus; positive regulation of NK T cell proliferation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of superoxide release; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of vascular permeability; regulation of cell adhesion; response to hypoxia; sleep; T-helper 1 type immune response

size1 :

0.01 mg

price1 :

205 USD

size2 :

0.05 mg

price2 :

465

size3 :

0.5 mg

price3 :

2080

more info or order :

MyBioSource product webpage