catalog number :
MBS8248168
products full name :
Anti-CD129 Antibody
products short name :
[CD129]
products name syn :
[Interleukin-9 receptor; IL-9 receptor; IL-9R; CD129]
other names :
[interleukin-9 receptor isoform 1; Interleukin-9 receptor; interleukin-9 receptor; interleukin 9 receptor; CD_antigen: CD129]
products gene name :
[IL9R]
other gene names :
[IL9R; IL9R; CD129; IL-9R; IL-9 receptor; IL-9R]
uniprot entry name :
IL9R_HUMAN
reactivity :
Human, Mouse
specificity :
Recognizes endogenous levels of CD129 protein.
purity :
The antibody was purified by affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1/500 - 1/2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD129. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to CD129
ncbi acc num :
NP_002177.2
ncbi gb acc num :
NM_002186.2
ncbi mol weight :
37,389 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); IL-9 Signaling Pathway (198883); Immune System Pathway (1269170); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Signaling By Interleukins Pathway (1269318)
ncbi summary :
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
IL9R: This is a receptor for interleukin-9. Belongs to the type I cytokine receptor family. Type 4 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: Xq28 and Yq12. Cellular Component: extracellular region; extracellular space; integral to plasma membrane. Molecular Function: interleukin-9 receptor activity. Biological Process: cell proliferation; signal transduction