Anti-p115 Antibody | MyBioSource MBS8247729 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-p115 Antibody

catalog :

MBS8247729

quantity :

0.05 mL

price :

175 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of p115 expression in BT474 (A), K562 (B), A549 (C) whole cell lysates.

image 2 :

Immunohistochemical analysis of p115 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

product information

catalog number :

MBS8247729

products type :

Antibody

products full name :

Anti-p115 Antibody

products short name :

[p115]

products name syn :

[VDP; General vesicular transport factor p115; Protein USO1 homolog; Transcytosis-associated protein; TAP; Vesicle-docking protein]

other names :

[general vesicular transport factor p115 isoform 1; General vesicular transport factor p115; general vesicular transport factor p115; USO1 vesicle transport factor; Protein USO1 homolog; Transcytosis-associated protein; TAP; Vesicle-docking protein]

products gene name :

[USO1]

other gene names :

[USO1; USO1; TAP; VDP; P115; VDP; TAP]

uniprot entry name :

USO1_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

973

specificity :

Recognizes endogenous levels of p115 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

app notes :

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/50 - 1/200. Immunoprecipitation: 1/20 - 1/50

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Immunogen: KLH-conjugated synthetic peptide of human p115

products description :

Rabbit polyclonal antibody to p115

ncbi gi num :

586798211

ncbi acc num :

NP_001276978.1

ncbi gb acc num :

NM_001290049.1

uniprot acc num :

O60763

ncbi pathways :

Arf1 Pathway (137927); Asparagine N-linked Glycosylation Pathway (1268714); COPI-mediated Anterograde Transport Pathway (1339109); COPII (Coat Protein 2) Mediated Vesicle Transport Pathway (1268727); Cell Cycle Pathway (1269741); Cell Cycle, Mitotic Pathway (1269763); ER To Golgi Anterograde Transport Pathway (1268726); Golgi Cisternae Pericentriolar Stack Reorganization Pathway (1269812); M Phase Pathway (1269810); Membrane Trafficking Pathway (1269877)

ncbi summary :

The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

uniprot summary :

TAP: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. Belongs to the VDP/USO1/EDE1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 4q21.1. Cellular Component: cytosol; endoplasmic reticulum; Golgi apparatus; Golgi membrane; Golgi stack; membrane; nucleolus; transport vesicle. Molecular Function: protein binding; protein transporter activity. Biological Process: COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; Golgi vesicle docking; intracellular protein transport; transcytosis

size1 :

0.05 mL

price1 :

175 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage