product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Anti-TUSC4 Antibody
catalog :
MBS8247530
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
image
image 1 :
Western blot analysis of TUSC4 expression in HL60 (A), U937 (B), mouse brain (C) whole cell lysates.
image 2 :
Immunofluorescent analysis of TUSC4 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
product information
catalog number :
MBS8247530
products type :
Antibody
products full name :
Anti-TUSC4 Antibody
products short name :
[TUSC4]
products name syn :
[TUSC4; Nitrogen permease regulator 2-like protein; NPR2-like protein; Gene 21 protein; G21 protein; Tumor suppressor candidate 4]
other names :
[nitrogen permease regulator 2-like protein; Nitrogen permease regulator 2-like protein; nitrogen permease regulator 2-like protein; NPR2-like, GATOR1 complex subunit; Gene 21 protein; G21 protein; Tumor suppressor candidate 4]
products gene name :
[NPRL2]
other gene names :
[NPRL2; NPRL2; NPR2; NPR2L; TUSC4; TUSC4; NPR2-like protein; G21 protein]
uniprot entry name :
NPRL2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
380
specificity :
Recognizes endogenous levels of TUSC4 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Ships on blue ice. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
Western Blot: 1/500 - 1/2000, Immunofluorescence/Immunocytochemistry: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant full length protein of human TUSC4
products description :
Rabbit polyclonal antibody to TUSC4
ncbi gi num :
50592992
ncbi acc num :
NP_006536.3
ncbi gb acc num :
NM_006545.4
uniprot acc num :
Q8WTW4
uniprot summary :
NPRL2: Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs. Belongs to the NPR2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Inhibitor; Tumor suppressor. Chromosomal Location of Human Ortholog: 3p21.3. Molecular Function: GTPase activator activity; protein binding; protein kinase activity. Biological Process: cellular response to amino acid starvation; negative regulation of kinase activity; negative regulation of TOR signaling pathway
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
245
size3 :
0.2 mL
price3 :
345
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments